Kasabach-Merritt phenomenon in a neonatal kaposiform haemangioendothelioma

Kasabach-Merritt phenomenon in a neonatal kaposiform haemangioendothelioma.

To cite: Mardegan V, Doglioni N, De Bernardo G, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014205855 DESCRIPTION A female infant was born at 27 weeks of gestation through emergency caesarean section, performed because of an acute increase of a compressive thoracic malformation diagnosed at the 20th gestational week. At birth, two enormous violaceous m...

[Kaposiform haemangioendothelioma with Kasabach-Merritt phenomenon].

Kasabach-Merritt phenomenon is a serious coagulopathy associated with kaposiform hemangioendothelioma (KHE), tufted angioma, and possibly other vascular neoplasms. KHE presenting in the absence of Kasabach-Merritt phenomenon is rare, although tufted angioma frequently occurs without thrombocytopenia. We retrospectively reviewed 10 cases of KHE without Kasabach-Merritt phenomenon. The tumors app...

Kaposiform Hemangioendothelioma in a Newborn with Kasabach-Merritt Syndrome

Kaposiform hemangioendothelioma with Kasabach-Merritt phenomenon: successful treatment with embolization and vincristine in two newborns.

Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor and has a high mortality in newborns when associated with Kasabach-Merritt syndrome (KMS). In two newborns with KHE and severe KMS refractory to medical treatment, emergency embolization led to clinical improvement in the acute neonatal setting by reducing tumor volume, increasing the platelet count, and improving other clotting par...

Sirolimus for treatment of kaposiform hemangioendothelioma associated with Kasabach-Merritt phenomenon

KHE: kaposiform hemangioendothelioma KMP: Kasabach-Merritt phenomenon INTRODUCTION Kaposiform hemangioendothelioma (KHE) was first described by Zuckerberg et al in 1992. KHE is defined as a rare, locally aggressive infiltrative vascular neoplasm that typically occurs during infancy and childhood. KHE generally originates on the skin as a distinctive cutaneous lesion with ill-defined borders, la...